@article{Faragó_Pšenáková_Faragová_2021, title={The use of biotechnology in hop (Humulus lupulus L.) improvement}, volume={9}, url={https://journals.scicell.org/index.php/NBC/article/view/1137}, DOI={10.36547/nbc.1137}, abstractNote={Hop (Humulus lupulus L.) is a clonally propagated, dioecious, perennial, climbing plant used commercially for their secondary metabolites. The resins containing α- and β-acids, and essential oils produced by the lupulin glands, present on the female flowers are used to add bitterness, aroma and flavour to beer. Recently, flavonoids, including chalcones and flavanones, of hops have been shown to exert a variety of biological activities, including oestrogenic and anticancerogenic characteristics. In this review, we provide a overview of the techniques and opportunities presented by the integration of plant biotechnology into hop improvement. The use of tissue culture techniques such as micropropagation, meristem culture, in vitro storage, adventitious shoot induction, callus culture and cell suspension culture in hops are briefly reviewed. The usefullness of genetic transformation technology to introduce novel traits into hop is also discussed. }, number={3}, journal={Nova Biotechnologica et Chimica}, author={Faragó, Juraj and Pšenáková, Ivana and Faragová, Natália}, year={2021}, month={Sep.}, pages={279–293} }