TY - JOUR AU - Hong Thien Van, AU - Tan Viet Pham, AU - Ngoc An Nguyen, AU - Hanh Thi Dieu Nguyen, AU - Quoc Hung Nguyen, AU - Thanh Tho Le, AU - Van Son Le, PY - 2022/08/17 Y2 - 2024/03/29 TI - Chemical profiles and antibacterial activities of acetone extracts of Globba macrocarpa JF - Nova Biotechnologica et Chimica JA - Nova Biotechnol. Chim. VL - 21 IS - 2 SE - Research Articles DO - 10.36547/nbc.1322 UR - https://journals.scicell.org/index.php/NBC/article/view/1322 SP - e1322 AB - <p><em>Globba macrocarpa</em> Gagnep. is a rare species of <em>Globba</em> genus (Zingiberaceae family). The present study reported the chemical compositions and antibacterial effects of acetone extracts obtained from the <em>G. macrocarpa</em> rhizomes and aerial parts. By using Gas Chromatography Mass Spectrometry (GC/MS) assay, fifty and thirty-two chemical compounds were identified from rhizomes and aerial parts of the species, respectively. Of those, germacrene D (15.25 %), 1H-indole, 4-(3-methyl-2-butenyl)- (14.33 %), <em>(E)-</em>β-farnesene (11.28 %), and 2-biphenylamine, 3-methyl (10.27 %) were the major constituents in the rhizome extract while the aerial part extract was characterized by the predominance of linolenic acid (19.89 %), palmitic acid (13.05 %), phytol (7.52 %), and neophytadiene (4.76 %). In addition, the rhizome extract had antibacterial activities against five 5 out of 6 oral bacteria, including <em>Pseudomonas aeruginosa</em>, <em>Salmonella enteritidis,</em> <em>Salmonella typhimurium Bacillus cereus</em>, and <em>Staphylococcus aureus. </em>Meanwhile, the aerial part extract was active against 4 out of 6 test bacteria, except for <em>Escherichia coli </em>and <em>S. typhimurium</em>.</p> ER -