Comparison of ten biochemical laboratory tests before and after treatment by statins

Authors

  • Tatiana Ďurčeková Department of Chemistry, University of SS. Cyril and Methodius, J. Herdu 2, Trnava, SK-917 01, Slovak Republic
  • Ján Mocák Department of Chemistry, University of SS. Cyril and Methodius, J. Herdu 2, Trnava, SK-917 01, Slovak Republic
  • Ján Balla Analytical-diagnostic laboratory, Kováčska 15, Prešov, SK-080 01, Slovak Republic
  • Gabriela Gromanová Analytical-diagnostic laboratory, Kováčska 15, Prešov, SK-080 01, Slovak Republic
  • Katarína Boronová Department of Chemistry, University of SS. Cyril and Methodius, J. Herdu 2, Trnava, SK-917 01, Slovak Republic

DOI:

https://doi.org/10.36547/nbc.1215

Keywords:

cardiovascular risk, lipid markers, statins, ROC curves, ANOVA, KNN classification

Abstract

Results of 10 biochemical tests of 172 patient data (among them 84 men data and 88 women data, resp.) before and after administration of statins were thoroughly studied. All monitored patients are characterized by disorders of lipoprotein metabolism or other kind of dislipidaemia. The calculations were performed using four chemometrical methods facilitating quantification and visualization of the statin effect upon most important biochemical parameters, mainly lipid markers, and allowing classification of the patient blood samples taking into account whether the patient has been or has not been medicated by a statin drug.

Downloads

Published

2021-11-22

How to Cite

Ďurčeková, T., Mocák, J., Balla, J., Gromanová, G., & Boronová, K. (2021). Comparison of ten biochemical laboratory tests before and after treatment by statins. Nova Biotechnologica Et Chimica, 9(2), 133-140. https://doi.org/10.36547/nbc.1215

Issue

Section

Research Articles
Received 2021-10-05
Published 2021-11-22