Applications substituted 2-aminothiophenes in drug design
Keywords:substituted 2-aminothiophenes, Gewald reaction, thieno[2,3-d][1,3]oxazin-4-ones, allosteric enhancers, 3-deazathiadiamine, drug design
AbstractHighly substituted thiophene derivatives are important heterocycles found in numerous biologically active compounds. Title compounds are attractive derivatives because their applications in pharmaceuticals, agriculture and pesticides. They exhibit antimicrobial activity against various Gram(+) and Gram(-) bacteria and fungi. Many of these molecules act as allosteric enhancers of A1-adenosine receptor, glucagon antagonists as well as antioxidant and anti-inflammatory agents.
How to Cite
Puterová, Z., Krutošíková, A., & Végh, D. (2021). Applications substituted 2-aminothiophenes in drug design. Nova Biotechnologica Et Chimica, 9(2), 167-173. https://doi.org/10.36547/nbc.1274
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