Chemical profile, antioxidant and photoprotective activities of essential oil and crude extracts of Algerian Thymus serpyllum

Authors

  • Nariman Madouni Bioconversion, Microbiological Engineering and Health Safety, SNV Faculty, Mustapha Stambouli University Sidi Said, Mascara 29000, Algeria
  • Boumediene Meddah Bioconversion, Microbiological Engineering and Health Safety, SNV Faculty, Mustapha Stambouli University Sidi Said, Mascara 29000, Algeria
  • Tir Touil Aicha Bioconversion, Microbiological Engineering and Health Safety, SNV Faculty, Mustapha Stambouli University Sidi Said, Mascara 29000, Algeria
  • Chawki Bensouici Centre de Recherche en Biotechnologie, Ali Mendjli, Nouvelle Ville UV 0.3, Constantine BP E73, Algeria
  • Yavuz S Cakmak Department of Biotechnology and Molecular Biology, Faculty of science and Letters, Aksaray University, Aksaray 68100, Turkey
  • Alessandra Piras Department of Chemical and Geological Sciences, University of Caligari, Citadella Universitaria, SP 8, Monserrato-Sestu Km 0.700, Monserrato (CA) 09042, Italy
  • Danilo Falconieri Department of Chemical and Geological Sciences, University of Caligari, Citadella Universitaria, SP 8, Monserrato-Sestu Km 0.700, Monserrato (CA) 09042, Italy
  • Pascal Sonnet AGIR Laboratory: Agents Infectieux, Résistance et Chimiothérapie, EA4294 UFR de Pharmacie, Université de Picardie Jules Verne, Amiens 80037, France

DOI:

https://doi.org/10.36547/nbc.916

Keywords:

Antioxidant, Essential oil, GC/MS, HPLC, Phenolic extracts , Thymus serpyllum

Abstract

Thymus serpyllum is an aromatic and medicinal plant widely used in Algerian folk medicine. It was collected from Mascara region North West of Algeria and studied in the aim to provide more knowledge about chemical composition, antioxidant and photo-protective activities of essential oil, ethanolic and infusion extracts. The chemical analysis of investigated T. serpyllum EO was performed for the first time in this research work. It was carried out by GC/MS for identifying 25 components where the dominated compounds were Carvacrol (66%) and γ–Terpinene (11.5%). The phenolic profile of ethanolic and aqueous infusion extracts was performed using HPLC chromatography and the data showed the Benzoic acid and Rosmarinc acid were found as major compounds. Extracts showed an excellent source of total phenols and flavonoids. Antioxidant activity was evaluated using DPPH, Galvinoxyl radical (GOR), CUPRAC, reducing power and O-phenanthroline approaches. All extracts showed a significant antioxidant capacity with different mechanisms. However, ethanol and infusion extracts showed stronger capacity than EO. Moreover, the photoprotective activity of T. serpyllum extracts was explored for the first time in our study. Extracts exhibited high values of sun protective factors (SFP) with 38.34±2.29 and 38.82±2.23 for ethanol and infusion extract respectively. Results of our study may encourage the pharmacologic, food and cosmetic sectors to use the wild thyme as natural and healthy source of active compounds.

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Published

2021-11-30

How to Cite

Madouni, N., Meddah, B. ., Aicha, T. T. ., Bensouici, C. ., Cakmak, Y. S. ., Piras, A. ., Falconieri, D. ., & Sonnet, P. (2021). Chemical profile, antioxidant and photoprotective activities of essential oil and crude extracts of Algerian Thymus serpyllum. Nova Biotechnologica Et Chimica, 20(2), e916. https://doi.org/10.36547/nbc.916

Issue

Section

Research Articles
Received 2021-03-20
Accepted 2021-08-16
Published 2021-11-30