Chemical profiles and antibacterial activities of acetone extracts of Globba macrocarpa
Keywords:Globba macrocarpa, GC/MS, Acetone extract, Antibacterial activities
Globba macrocarpa Gagnep. is a rare species of Globba genus (Zingiberaceae family). The present study reported the chemical compositions and antibacterial effects of acetone extracts obtained from the G. macrocarpa rhizomes and aerial parts. By using Gas Chromatography Mass Spectrometry (GC/MS) assay, fifty and thirty-two chemical compounds were identified from rhizomes and aerial parts of the species, respectively. Of those, germacrene D (15.25 %), 1H-indole, 4-(3-methyl-2-butenyl)- (14.33 %), (E)-β-farnesene (11.28 %), and 2-biphenylamine, 3-methyl (10.27 %) were the major constituents in the rhizome extract while the aerial part extract was characterized by the predominance of linolenic acid (19.89 %), palmitic acid (13.05 %), phytol (7.52 %), and neophytadiene (4.76 %). In addition, the rhizome extract had antibacterial activities against five 5 out of 6 oral bacteria, including Pseudomonas aeruginosa, Salmonella enteritidis, Salmonella typhimurium Bacillus cereus, and Staphylococcus aureus. Meanwhile, the aerial part extract was active against 4 out of 6 test bacteria, except for Escherichia coli and S. typhimurium.
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Copyright (c) 2022 Hong Thien Van, Tan Viet Pham, Ngoc An Nguyen, Hanh Thi Dieu Nguyen, Quoc Hung Nguyen, Thanh Tho Le, Van Son Le
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