Antagonostic effectiveness of Macromycetes against Candida albicans strains and Issatchenkia orientalis

Authors

  • Victor Barshteyn Institute of Food Biotechnology and Genomics of the National Academy of Sciences of Ukraine
  • Tetiana Krupodorova Institute of Food Biotechnology and Genomics of the National Academy of Sciences of Ukraine
  • Olena Pokas Institute of Epidemiology and Infectious Diseases of the National National Academy of Medical Sciences of Ukraine

DOI:

https://doi.org/10.36547/nbc.760

Keywords:

Dual-culture plate assay , Macromycetes, Saccharomycetaceae, Species interactions

Abstract

The trend to search novel natural antifungal compounds has recently been increasing. Interspecific interactions between 30 Macromycetes species and fungal pathogens (Issatchenkia orientalis, Candida albicans strains) have been evaluated using dual culture plate assay. Interaction reactions between studied fungi were different: deadlock after mycelia contact or at a distance, overgrowth without initial deadlock, partial or complete replacement after initial deadlock with contact. Domination of replacement (78.7 %) of pathogenic fungi by Macromycetes was established. Complete replacement was almost twice more frequent (30.7 %) than partial replacement (19.3 %). These results clearly indicate effectiveness of Macromycetes against pathogenic fungi via contact antagonism. Strong antagonistic activity with high antagonistic index (AI) was established by xylotrophic species Ganoderma applanatum (AI = 22.5), Lentinula edodes (AI = 21.0), Flammulina velutipes, Irpiciporus litschaueri and Pleurotus ostreatus (AI = 20.5), leaf litter decay fungus Crinipellis schevczenkoi (AI = 21), and soil saprotroph   Lyophyllum shimeji (AI = 21).

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Published

2021-06-23

How to Cite

Barshteyn, V., Krupodorova, T. ., & Pokas, O. . (2021). Antagonostic effectiveness of Macromycetes against Candida albicans strains and Issatchenkia orientalis. Nova Biotechnologica Et Chimica, 20(1), e760. https://doi.org/10.36547/nbc.760

Issue

Section

Research Articles
Received 2020-11-18
Accepted 2021-04-21
Published 2021-06-23